Maryam Mohammad is a fifth-year medical student at UAEU who co-authored this research under the mentorship of Professor Musthaq Khan], a specialist in microbiology with a focus on antimicrobial resistance. has published extensively on nosocomial infections and bacterial genomics. Together, they aim to provide insights into combating multidrug-resistant pathogens, contributing to the global fight against infectious diseases.
Enterobacter hormaechei is a significant nosocomial pathogen associated with multidrug resistance. This study investigates high-risk clones isolated from tertiary care hospitals using whole-genome sequencing (WGS). The findings reveal diverse resistance genes, mobile genetic elements, and virulence factors contributing to its pathogenicity. Comparative genomics identified clonal relationships and novel plasmids driving antimicrobial resistance. These results highlight the urgent need for stringent infection control policies and novel therapeutic approaches to combat E. hormaechei-associated infections.Enterobacter hormaechei is a significant nosocomial pathogen associated with multidrug resistance. This study investigates high-risk clones isolated from tertiary care hospitals using whole-genome sequencing (WGS). The findings reveal diverse resistance genes, mobile genetic elements, and virulence factors contributing to its pathogenicity. Comparative genomics identified clonal relationships and novel plasmids driving antimicrobial resistance. These results highlight the urgent need for stringent infection control policies and novel therapeutic approaches to combat E. hormaechei-associated infections.