Over the past decades, the increase of multidrug-resistant (MDR) forms of Salmonella in food-producing animals has progressively become a serious risk worldwide (1). This is likely due to the widespread and long term use of common antimicrobials in poultry and animal husbandry for therapeutics, prophylaxis and growth promotion 2 Although Salmonella is a major cause of human foodborne illnesses worldwide, little is known about its phenotypic and genotypic characteristics in food sources in Saudi Arabia Therefore, this study investigated genotypic and phenotypic antimicrobial resistance profiles, phylogenic relatedness, plasmid and virulence composition of 39 Salmonella enterica strains isolated from chicken meat samples using whole genome sequencing (WGS) technology.