Motahra Mahi Birjand is a 34-year-old from Iran, and I graduated from Shiraz University of Medical Sciences with a Ph.D. doctorate in clinical pharmacy in May 2020. My journey in academia has been genuinely fulfilling. I am currently serving as an Assistant Professor of clinical pharmacy at the Faculty of Pharmacy in Birjand University of Medical Sciences and member of Infectious Diseases Research Center, Birjand University of Medical Sciences. I am highly grateful for the opportunity to speak at this congress, and I am eager to contribute to the discussions and share my knowledge and expertise.
Antimicrobial prophylaxis used for surgical procedures remains one of the measures for preventing surgical site infections (SSIs). The present study was designed to assess compliance with clinical practice guidelines for antimicrobial prophylaxis in variable surgeries conducted in the intensive care units (ICUs) of a major referral hospital. This cross-sectional investigation was carried out using prospective data collected from October 2017 to March 2018 in the intensive care unit (ICU) of Nemazi Hospital in Shiraz. Demographic characteristics, surgery type, and antibiotic treatment were gathered from medical records and entered into data collection forms. We reviewed compliance and adherence to prophylactic antibiotic administration to the Infectious Diseases Society of America (IDSA) guidelines and evaluated the courses of antimicrobial drugs. If an antibiotic administrated for surgical prophylaxis differed from the guideline, the antibiotic was classified as a non-guideline-based antibiotic. Most patients who participated in this study were male (64.5%). Only 8.75% of the administrated antibiotics chosen for surgical prophylaxis were found to be appropriate antibiotic prescriptions; however, those patients receiving appropriate antibiotics prescribed an inappropriate dosage. In addition, the antibiotics were administrated with inappropriate durations in all cases. Our findings indicated that adherence to the IDSA international guideline seems far from ideal in Namazi Hospital for antimicrobial prophylaxis, resulting in the unsuitable administration of various antibiotics.