Speakers - 2024

Biography

• I am an ECFMG-certified graduate from New Delhi, India. After graduating from medical school, I did a postgraduation residency in Ophthalmology in New Delhi, India. For the past three years, I have been training in Internal Medicine both in India and the USA, as I wish to pursue a career in Internal Medicine. I was privileged to complete one month of clinical rotation in the Infectious Disease Division at TTUHSC, during which I contributed to the writing of this interesting case report, under the guidance of esteemed faculty.

Abstract

Abstract:
A 44-year-old gentleman with morbid obesity and undiagnosed diabetes presented with the signs and symptoms of diabetic ketoacidosis (DKA) and sepsis secondary to necrotizing soft tissue infection of the right side of the perineum and scrotum. He received treatment for DKA along with broad spectrum intravenous (IV) antibiotic coverage including vancomycin, clindamycin and piperacillintazobactam (P/T) and underwent surgical debridement to the gangrenous wound. The wound cultures from the perineum grew Streptococcus agalactiae, Streptococcus anginosus and Prevotella bivia, while the blood culture grew Alloscardovia omnicolens. At this point, antibiotics were adjusted to IV linezolid and P/T. The infectious disease service was consulted and recommended P/T for two weeks in view of Alloscardovia omnicolens bacteremia. A. omnicolens has been found to be a normal commensal of the oral cavity and the gastrointestinal tract [1]; however, it has also been isolated from a variety of specimens, including pleural fluid in thoracic empyema, blood, urethra and urine. [[1],[2]]. There is limited data on the clinical significance of A. ominicolens; however, there have been quite a few case reports on isolation of A. ominicolens in urine of patients with UTIs [[1],[3],[4]]. It is noteworthy to find bacteremia due to A. omnicolens in the setting of Fournier gangrene.

Keywords: Alloscardovia omnicolens, Fournier gangrene, Necrotizing soft tissue infections

Statements and Declarations: The authors have no competing interests to declare that are relevant to the content of this article.

Acknowledgements: This work was supported by the Division of Infectious Disease, Texas Tech University Health Science Center

References:
1. Mahlen, S.D. and J.E. Clarridge, 3rd, Site and clinical significance of Alloscardovia omnicolens and Bifidobacterium species isolated in the clinical laboratory. J Clin Microbiol, 2009. 47(10): p. 3289-93.
2. Takiguchi, Y., et al., Thoracic empyema caused by Alloscardovia omnicolens and Bifidobacteriumdentium. J Infect Chemother, 2022. 28(11): p. 1567-1570.
3. Brown, M.K., et al., Defining the Clinical Significance of Alloscardovia omnincolens in the Urinary Tract. J Clin Microbiol, 2016. 54(6): p. 1552-1556.
4. Lainhart, W. and M. Gonzalez, Aerococcus urinae, Alloscardovia omnicolens , and Actinotignum schaalii : the AAA Minor League Team of Urinary Tract Infection Pathogens. Clinical Microbiology Newsletter, 2018. 40: p. 77-82.